Bone scans are widely utilized for detection of metastases from bone sarcomas. Technetium methylene diphosphonate scan ([99mTc]MDP) is one of the most popular radiotracers used for that purpose. Lymphatic spread of bone sarcomas is unusual and often difficult to diagnose. Unfortunately, bone scans are not as sensitive in demonstrating lymphatic spread of sarcomas as they are at demonstrating hematogenous spread. A bone scan will often fail to demonstrate lymph nodes metastases until there is mineralization at the affected node. In this report, we highlight an interesting case of a patient with secondary osteogenic sarcoma (OS) from Pagets disease in the distal femur with non-ossified inguinal nodal metastasis diagnosed with [99mTc]MDP. Lymph node involvement was not appreciated on plain radiographs or computed tomography (CT).

Author

Alexandre Arkader and Carol D. Morris

Contact Details

Corresponding address:
Alexandre Arkader, MD, Children's Orthopaedic Center, Children's Hospital Los Angeles,
4650W Sunset Blvd, Mailstop #69, Los Angeles, CA 90027, USA

Reference

ICIS Cancer Imaging Volume 8 Issue 1
DOI: 10.1102/1470-7330.2008.0021

Date Posted

25 June 2008

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