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The effect of tamoxifen on the genital tract
Abstract
Tamoxifen is a selective estrogen receptor modulator (SERM) that is widely used in the treatment of patients with
breast cancer and for chemoprophylaxis in high risk women. Tamoxifen results in a spectrum of abnormalities
involving the genital tract, the most significant being an increased incidence of endometrial cancer and uterine
sarcoma. This article reviews the effects of tamoxifen on the genital tract and the strengths and weaknesses of various
imaging modalities for evaluating the endometrium.
Author
Sandra A. Polin and Susan M. Ascher
Contact Details
Corresponding address: Sandra A. Polin, MD, Department of Radiology, Georgetown University Hospital,
3800 Reservoir Road, Washington, DC 20007, USA
Reference
ICIS Cancer Imaging Volume 8 Issue 1
DOI: 10.1102/1470-7330.2008.0020
Date Posted
30 June 2008
Open Access is provided for this article.
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