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MRI features of intrahepatic extramedullary haematopoiesis in sickle cell anaemia
Abstract
Extramedullary haematopoiesis (EMH) is a reactive mechanism by
which blood cells are produced outside of the bone marrow to
supplement insufficient production or increased destruction of
erythrocytes. EMH is uncommon in sickle cell anaemia (SCA). We
report the first case of focal intra-hepatic EMH in SCA depicted
on MRI occurring in a 32-year-old woman with homozygote SCA and
in view of previously published data, highlight the diagnostic
features suggesting a differential diagnosis with other focal
liver lesions including infectious, inflammatory or primary
liver tumors.
Author
Mohamed Ali Jelali, Alain Luciani, Hicham Kobeiter, Serge Zafrani, Marie Christine Anglade, Benhalima Zegai, Dora Bachir and Alain Rahmouni
Contact Details
Corresponding address: Alain Luciani MD,
Service d'Imagerie Medicale,
Hopital Henri Mondor, 51,
avenue du Marechal de Lattre de Tassigny,
94010 Creteil cedex, France
Reference
ICIS Cancer Imaging Volume 6 Issue 1
DOI: 10.1102/1470-7330.2006.0030
Date Posted
28 November 2006
Open Access is provided for this article.
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