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Functional magnetic resonance imaging for defining the biological target volume
Abstract
Morphology as demonstrated by CT is the basis for radiotherapy
planning. Intensity-modulated and adaptive radiotherapy
techniques would greatly benefit from additional functional
information allowing for definition of the biological target
volume. MRI techniques include several which can characterize
and quantify different tissue properties and their
tumour-related changes. Results of perfusion MRI represent
microvascular density and permeability; MR spectroscopy depicts
particular metabolites; diffusion weighted imaging shows tissue
at risk and tumour cellularity; while dynamic 3D acquisition (4D
MRI) shows organ motion and the mobility of tumours within them.
Author
Hans-Ulrich Kauczor, Christian Zechmann, Bram Stieltjes and Marc-Andre Weber
Contact Details
Corresponding address:
Prof Hans-Ulrich Kauczor, MD,
Department of Radiology,
Innovative Cancer Diagnostics and Therapy,
German Cancer Research Center,
Im Neuenheimer Feld 280,
69120 Heidelberg,
Germany
Reference
ICIS Cancer Imaging Volume 6 Issue 1
DOI: 10.1102/1470-7330.2006.0010
Date Posted
1 June 2006
Open Access is provided for this article.
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