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The sentinel node in gynaecological malignancies
Abstract
As lymph node metastasis is one of the earliest features of
tumour cell spread in most human cancers, assessment of the
regional lymph nodes is required for tumour staging, determining
prognosis and planning adjuvant therapeutic strategies. However,
complete lymph node dissections are frequently associated with
significant complications. Conjugating the diagnostic advantages
with decreased morbidity, the sentinel node concept represents
one of the most recent advances in surgical oncology. In this
review we briefly highlight the historical background of the
development of the sentinel node concept, the anatomical
evidence for applying the sentinel node concept in pelvic
gynaecological cancers and the technical aspects of sentinel
node detection. We discuss recent studies in vulval, cervical
and endometrial cancer.
Author
J Balega and P O Van Trappen
Contact Details
Corresponding address:
P O Van Trappen,
The Gynaecological Cancer Centre,
St Bartholomew's Hospital,
West Smithfield, London,
EC1A 7BE, UK
Reference
ICIS Cancer Imaging Volume 6 Issue 1
DOI: 10.1102/1470-7330.2006.0002
Date Posted
28 February 2006
Open Access is provided for this article.
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